Try to restart the device itself and the try with the settings disabled. This is needed since the noise actually comes from the iOS itself and not from the application and could be triggered from and event or an application (not only Zoiper). With the restart of the device its state will be change in a way where this noise is not yet triggered.
As for the automatic registration, note that if there is a drop of the connection or a network change then the registration might be lost. Or there is another option, when TCP or TLS is used the server is sending wake up packets, but according to a regulation from Apple for iOS, if the wake-ups exceed the number of 15 packets for 300 seconds the iOS system will kill the application in order to preserve battery.